Heredity in Ichthyosis
نویسنده
چکیده
A case of advanced ichthyosis was recently admitted into the Windham Hospital. The family history as far as it could be elicited made it apparent that it was a disease of the males in the family transmitted through the females, the latter being immune. The patient's elder brother was suffering from the same disease, while his sisters were all free; his father did not suffer from it, nor his grandfather so far as could be ascertained. Both his mother and her sister were unaffected, but the latter's two sons had the disease while her
منابع مشابه
Characterization of bovine TGM1 and exclusion as candidate gene for ichthyosis in Chianina.
Ichthyosis is a heterogeneous group of keratinization disorders reported both in human and animals. Two rare, inherited forms have been reported in cattle, both characterized by autosomal recessive transmission. Because mutations of transglutaminase 1 (TGM1) gene are associated with autosomal recessive ichthyosis in people, this gene was investigated as a candidate for the diseases in cattle. T...
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